MET Mutation Detection Kit

Qualitative detection of exon 14 skipping mutation in MET gene.
MET alterations that result in exon 14 skipping are found in approximately 3~4% of lung adenocarcinoma patients. Exon 14 skipping results in the deletion of the juxtamembrane domain of MET, which leads to enhanced signaling through the MET receptor pathway. Studies have shown that NSCLC patients harboring MET with exon 14 skipping have increased sensitivity to MET-targeted therapies, such as crizotinib, cabozantinib, etc..
MET Mutation Detection Kit is a real-time PCR assay for qualitative detection of exon 14 skipping mutation in MET gene in human total RNA extracted from NSCLC formalin-fixed paraffin-embedded (FFPE) tissue samples.

Categorieën: ,


Cat. nr: 3511X024

Number of tests: 24

Name: MET Mutation Detection Kit

Sample type: FFPE tissue

Compatible instruments

  • SLAN-96
  • ABI7500
  • Rotor-Gene Q
  • Mx3000P
  • LightCycler 480 II



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